These guidelines for laboratory services are contained in a series of three manuals, two of which are focused on the technical aspects of tuberculosis microscopy and culture and a third which deals with laboratory management, including aspects such as laboratory safety and proficiency testing. These manuals have been developed for use in low-and middle-income countries with high tuberculosis prevalence and incidence rates...
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Lab Personnel
1998
This notice explains that on September 30, 1999, the Food and Drug Administration approved a reformulated amplified Mycobacterium Tuberculosis Direct (MTD) test for detection of Mycobacterium tuberculosis in acid-fast Bacille (AFB) smear-positive and smear-negative respiratory specimens from patients suspected of having TB.
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Lab Personnel
2000
This training manual is expected to help trainers in conducting the practical training of Acid Fast Bacilli (AFB) microscopy. For this purpose, only the essential components of microscopy practice are described in the order of the training process and in the simplest and most practical manner. Also, this material will help trainers and trainees to identify problems or weaknesses in their practice and determine ways to overcome them.
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International Agencies
Lab Personnel
2005
This fact sheet uses a question-and-answer format to provide the general public with information on TB. It discusses TB disease and infection, transmission, symptoms, diagnosis, and treatment.
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2005
This is the second edition of the "Red Book". It provides guidance to national tuberculosis programmes and the laboratory network on the role of TB laboratory services. It outlines the main responsibilities within the network and the technical and organisational aspects of microscopic sputum-smear examination and the surveillance of anti-tuberculosis drug resistance...
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International Agencies
Lab Personnel
2007
This document is intended for those dealing with tuberculosis and HIV at all levels in HIV-prevalent and resource-constrained settings. It is intended to assist development of national policies to improve the diagnosis and management of smear-negative pulmonary and extrapulmonary tuberculosis. The recommendations and algorithms are designed for use by national tuberculosis and HIV/AIDS control programs and service providers.
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International Agencies
Managers and Supervisors
2007
This document describes nineteen (19) new or improved diagnostic tools of the many that have been or are being developed. WHO has a process for evaluating and endorsing new tools for TB control programmes. Three (3) of the tools described in this document have already been endorsed by WHO and are being implemented by countries, while the others are still under development or in piloting phase and are expected to be ready for review for appropriateness for scaled-up use in the coming years...
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Lab Personnel
Policy Makers
2008
This report describes the updated guidelines for using nucleic acid amplification tests in the diagnosis of tuberculosis (TB).
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Lab Personnel
2009
This pamphlet provides detailed guidelines for patients about how and when to collect a sputum sample.
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2009
This website is a comprehensive source of evidence syntheses, policies, guidelines, and research agendas on TB diagnosis. The website offers detailed guidance on how to conduct and report diagnostic research on TB, guidance on how to perform systematic reviews of diagnostics, tools on guideline development, including GRADE, and documents on improvement of laboratory quality and practice...
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Lab Personnel
2009
This video provides a step-by-step guide for patients on how to collect sputum at home. The video is available in 18 languages (Burmese, English, French, Hmong, Karen, Karenni, Khmer, Kunama, Lao, Mandarin Chinese, Nepali, Russian, Somali, Spanish, Swahili, Tigrinya, Urdu, and Vietnamese).
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General Public
2011
This fact sheet illustrates the timeline for various treatment regimens and monitoring techniques for persons with TB. It includes a timeline for drug regimens, providers, visits, sputum specimens, chest X-rays, and baseline and follow-up test.
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2012
This guide was developed by the Global Laboratory Initiative, which is one of the Working Groups of the Stop TB Partnership. The guide replaces both the 1998 WHO and 2000 IUATLD guides on smear microscopy and contains many new elements.
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Lab Personnel
2013
This series of interactive modules was developed by the Association of Public Health Laboratories (APHL) in collaboration with the Centers for Disease Control and Prevention. Topics include laboratory safety, specimen collection, AFB smear microscopy, mycobacterial culture, and drug susceptibility testing...
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Lab Personnel
2014
This resource is designed to help facilitate a training of The Union's "Online Childhood TB Training for Healthcare Workers course" (https://childhoodtb.theunion.org). Included in the training package are a facilitator's guide, sample course agenda, a participant workbook, and a sample evaluation form...
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2017
