TB Elimination: Treatment Options for Latent Tuberculosis Infection

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This information sheet discusses treatment for individuals with latent tuberculosis infection (LTBI), with the purpose of this treatment being the reduction of the risk that the infection will progress to TB disease. It explains how the health care provider determines whether the individual with a positive tuberculin skin test (TST) or blood test result is a candidate for treatment of LTBI and how the most effective regimen is chosen; presents LTBI treatment regimens; and describes monitoring during treatment, drug-drug interactions, particularly for HIV-infected patients, and side effects.